Time：4:00-5:30 PM，Tues.，July 6，2021

Venue: Room 312, 3F, Building 3,  Yunqi Campus

Host：Dr. Qi Xie, School of Life Sciences

Speaker:

Dr. Zhenyu Zhong 

Assistant Professor, Department of Immunology, UT Southwestern Medical Center

Dr.

Dr. Zhenyu Zhong is an Assistant Professor in the Department of Immunology at UT Southwestern Medical Center. His laboratory centers at understanding how inflammation is initiated, propagated and terminated, as well as how dysregulation of inflammation promotes disease development. Prior to joining UT Southwestern, Dr. Zhong was a postdoctoral fellow at UC San Diego, where he made several fundamental discoveries that had established “mitochondria” as the command center for innate immunity. Dr. Zhong has received many prestigious awards, including an NIH MIRA R35 Award, a Milstein Young Investigator Award from International Cytokine and Interferon Society, a Pinnacle Research Award from American Association for the Study of Liver Diseases, a CPRIT Faculty Recruitment Award, a UT System Rising Star Award, an NIH K22 Career Transition Award, and an American Association of Immunologists Trainee Achievement Award, among others.

Abstract:

A transient and properly controlled immune response is crucial for restoring homeostasis after tissue damage, while its absence often causes immunopathology. The research of my laboratory centers at dissecting the fundamental mechanisms by which inflammation is initiated, propagated and terminated when no longer needed. We are also interested in understanding how dysregulated inflammation promotes disease development. In this seminar talk, we will review novel mechanistic insights of inflammation initiation and termination. Additionally, we will discuss how dietary obesity dismantles immune homeostasis in the liver, thereby causing chronic hepatic inflammation that drives the development of non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC).

Contact：

Wenyue Yu：yuwenyue@westlake.edu.cn

School of Life Sciences